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Updated: May 7, 2026

Chemical Triphosphorylation of Oligonucleotides
Published on: June 2, 2022
O,O-Dimethyl O-(4-sulfamoylphen-yl) phospho-rothio-ate (cythio-ate)
Puhan Zhao1, Russell G Baughman
1Department of Chemistry, Truman State University, Kirksville, MO 63501-4221, USA.
Abstract:
The title mol-ecule, C8H12NO5PS2, exhibits a crystallographic mirror plane that is perpendicular to the ring and bis-ects the sulfamoyl and thio-phosphate ester groups. In the crystal, mol-ecules are linked by N-H⋯O hydrogen-bonding inter-actions reminiscent of carb-oxy-lic acid hydrogen bonding pairs, forming chains parallel to the b-axis direction.
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