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Updated: May 7, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
3-({[Bis(2-methyl-prop-yl)carbamo-thio-yl]amino}-carbon-yl)benzamide
N Selvakumaran1, R Karvembu, Seik Weng Ng
1Department of Chemistry, National Institute of Technology, Tiruchirappalli 620 015, India.
Abstract:
In the title compound, C17H25N3O2S, the terminal and central amide groups are, respectively, twisted and coplanar with the attached benzene ring [O-C-C-C torsion angles = 22.7 (3) and 5.4 (3)°]. In the central part of the mol-ecule, the amide and thio-amide residues are approximately perpendicular [C-N-C-S torsion angle = -104.98 (18)°]. Supra-molecular layers with a zigzag topology are formed in the crystal packing by N-H⋯O, N-H⋯S and C-H⋯O inter-actions; these stack along c, being separated by hydro-phobic inter-actions.
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