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Related Experiment Video

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Standardized Rat Coronary Ring Preparation and Real-Time Recording of Dynamic Tension Changes Along Vessel Diameter

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Published on: June 16, 2022

[Testosterone and coronary artery disease].

Asier Leibar Tamayo¹, Ander Astobieta Odriozola, Eduardo García-Cruz

¹Urology Department. Hospital Galdakao-Usansolo.Guipuzcoa. Sexual Medicine Unit. Urologia Clinica Bilbao.Spain.

Archivos Espanoles De Urologia

|September 20, 2013

Summary

Testosterone Deficit Syndrome (TDS) is common in elderly men and linked to cardiovascular disease (CAD). This case study highlights managing a patient with both conditions, emphasizing diagnosis and treatment for improved outcomes.

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Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)

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Published on: May 2, 2012

Area of Science:

Endocrinology
Cardiology
Geriatrics

Background:

Testosterone Deficit Syndrome (TDS) is prevalent in elderly men, often coexisting with comorbidities like diabetes and obesity.
These comorbidities are known risk factors for coronary artery disease (CAD) and arteriosclerosis.
A correlation between TDS and increased CAD prevalence is supported by multiple studies.

Observation:

A 64-year-old male with hypertension, diabetes, and obesity presented with erectile dysfunction and low libido.
Initial tests revealed low total testosterone (150 ng/dl) and low HDL cholesterol (30 mg/dl).
The patient also reported exertional chest pain, indicative of potential CAD.

Findings:

The patient underwent a stress test positive for angina, leading to a coronary angiogram.
A severe lesion (85%) in the anterior descending artery was identified and treated with balloon angioplasty and stenting.
Combined therapy with testosterone and a PDE5 inhibitor was initiated for his hormonal and erectile dysfunction symptoms.

Implications:

This case illustrates the importance of evaluating for TDS in elderly men with cardiovascular risk factors and vice versa.
Integrated management addressing both TDS and CAD is crucial for comprehensive patient care.
Early diagnosis and treatment of TDS and CAD can improve patient quality of life and cardiovascular outcomes.