Acute coronary syndrome
Nader Makki1, Theresa M Brennan2, Saket Girotra3
1Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Insights
Acute coronary syndrome (ACS) causes over 1 million US hospitalizations yearly, posing a significant health and economic burden. This review summarizes ACS pathophysiology, diagnosis, and treatment, including intensive care management of complications.
Area of Science:
- Cardiology
- Internal Medicine
- Critical Care Medicine
Background:
- Acute coronary syndrome (ACS) represents a substantial healthcare and economic challenge in the US.
- ACS leads to over 1 million hospitalizations annually.
- Nearly 50% of coronary heart disease deaths are linked to ACS events.
Purpose of the Study:
- To provide an updated review of acute coronary syndrome.
- To summarize the pathophysiology, diagnosis, and treatment of ACS.
- To offer guidance on managing common complications and hemodynamic disturbances in intensive care settings.
Main Methods:
- Literature review of current research on ACS.
- Synthesis of information on ACS pathophysiology.
- Compilation of diagnostic and therapeutic strategies for ACS.
Main Results:
- ACS is a critical condition with significant morbidity and mortality.
- Comprehensive understanding of ACS pathophysiology is essential for effective management.
- Timely diagnosis and appropriate treatment, including intensive care, improve patient outcomes.
Conclusions:
- This review offers a consolidated overview of ACS.
- It emphasizes the importance of up-to-date knowledge for clinicians managing ACS.
- Effective management strategies are crucial to reduce the substantial burden of ACS.
Abstract:
Acute coronary syndrome (ACS) is a major health care and economic burden in the United States and accounts for more than 1 million hospitalizations annually. The morbidity and mortality due to ACS are substantial-nearly half of all deaths due to coronary heart disease occur following an ACS. This review provides an up-to-date summary of the pathophysiology, diagnosis, and treatment of ACS. We also provide an overview of the management of common hemodynamic disturbances and myocardial infarction complications that physicians often encounter in an intensive care setting.
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