Related Experiment Video
Updated: May 7, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Stage IV lung cancer: Is cure possible?
Ravi Thippeswamy1, Vanita Noronha, Vamshi Krishna
1Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.
This case report discusses a 53-year-old male with stage IV non-small cell lung cancer and malignant pleural effusion. It highlights the limited literature on surgical management for this specific condition, often treated palliatively.
Area of Science:
- Oncology
- Thoracic Surgery
Background:
- Stage IV non-small cell lung cancer (NSCLC) is typically managed with palliative intent.
- Treatment modalities for advanced NSCLC often include chemotherapy, radiotherapy, and occasionally surgery.
- Oligometastatic NSCLC data primarily focuses on adrenal or brain metastases.
Observation:
- A case of a 53-year-old male with stage IV NSCLC presenting with cytologically proven malignant pleural effusion is reported.
- Malignant pleural effusion in stage IV NSCLC presents a complex management scenario.
Findings:
- Surgical management of stage IV NSCLC with pleural effusion is rarely documented in existing literature.
- The scarcity of data suggests a gap in understanding the role of surgery in this specific metastatic context.
Implications:
- This case contributes to the limited body of knowledge regarding surgical interventions for stage IV NSCLC with pleural effusion.
- Further research is warranted to explore the potential benefits and risks of surgical management in such cases.
Related Concept Videos
Treatment Resistant Cancers
Tumor Immunotherapy
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...