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Updated: Feb 15, 2026
09:41
An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
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Multiple Myeloma Presenting as Thyroid Plasmacytoma
Kaalindi Singh1, Pankaj Kumar1, Ritesh Pruthy2
1Department of Radiation Oncology, Max Super Speciality Hospital, Mohali, Punjab, India.
Summary
Multiple myeloma rarely infiltrates the thyroid gland. This case highlights a patient initially diagnosed with extramedullary thyroid plasmacytoma, later confirmed as multiple myeloma with thyroid involvement.
Area of Science:
- Oncology
- Endocrinology
- Pathology
Background:
- Multiple myeloma (MM) is a plasma cell malignancy.
- Extramedullary involvement, particularly in the thyroid, is uncommon in MM.
Observation:
- A patient presented with hoarseness and a thyroid lesion involving cartilage.
- Initial diagnostics ruled out MM, suggesting extramedullary plasmacytoma of the thyroid.
Findings:
- Subsequent imaging revealed bone lesions, leading to a diagnosis of MM with thyroid infiltration.
- This case underscores the diagnostic challenges of extramedullary plasmacytoma in the thyroid.
Implications:
- Highlights the importance of comprehensive staging in suspected extramedullary plasmacytomas.
- Emphasizes the need to consider MM even with initial negative results for systemic disease.
- Informs diagnostic and treatment strategies for rare thyroid involvement in multiple myeloma.
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