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Serum Laboratory Studies, Stool Test, Breath Test

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...

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Updated: May 23, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

Liquid Biopsy and Colorectal Cancer.

Shyam Aggarwal¹, Anuradha Chougle², Vineet Talwar³

¹Department of Medical Oncology, Sir Ganga Ram Hospital, New Delhi, India.

South Asian Journal of Cancer

|March 10, 2025

Summary

This summary is machine-generated.

Liquid biopsy offers a noninvasive approach for frequent sampling in colorectal cancer (CRC) patients. This method aids in early diagnosis, screening, treatment monitoring, and identifying metastasis through molecular and exosomal RNA analysis.

Keywords:

biomarker driver mutations minimal residual disease molecular monitoring

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Last Updated: May 23, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

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Published on: June 8, 2020

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer

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Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing

Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing

Published on: September 25, 2011

Area of Science:

Oncology
Molecular Biology
Genetics

Background:

Colorectal cancer (CRC) frequently metastasizes, necessitating personalized management strategies.
Current methods for monitoring CRC metastasis often require invasive procedures.
Noninvasive techniques for frequent patient sampling are crucial for optimizing CRC care.

Purpose of the Study:

To review the current applications of liquid biopsy in colorectal cancer (CRC).
To highlight the role of liquid biopsy in early diagnosis, screening, and treatment follow-up for CRC.
To discuss the potential of liquid biopsy in detecting molecular changes, microbiota, and exosomal RNA in CRC.

Main Methods:

Literature review of studies on liquid biopsy in colorectal cancer.
Analysis of liquid biopsy applications including early diagnosis, screening, and patient monitoring.
Exploration of emerging liquid biopsy biomarkers such as microbiota and exosomal RNA.

Main Results:

Liquid biopsy is a valuable noninvasive tool for CRC management.
Serial sampling via liquid biopsy enhances early detection of progression and treatment response.
Liquid biopsy shows promise in identifying tumor-associated microbiota and exosomal RNA.

Conclusions:

Liquid biopsy is increasingly important for personalized management of colorectal cancer.
Its applications span early detection, screening, monitoring treatment, and identifying progression.
Future directions include analyzing microbiota and exosomal RNA for improved CRC patient care.