Related Experiment Video
Updated: May 7, 2026

Photostimulation by Femtosecond Laser Activates Extracellular-signal-regulated Kinase (ERK) Signaling or Mitochondrial Events in Target Cells
Published on: July 6, 2019
From stealing fire to cellular reprogramming: a scientific history leading to the 2012 Nobel Prize
M William Lensch1, Christine L Mummery
1Department of Pediatrics, Harvard Medical School, 250 Longwood Avenue, Boston, MA 02115, USA ; Division of Hematology/Oncology, Howard Hughes Medical Institute/Boston Children's Hospital, 1 Blackfan Circle, Boston, MA 02115, USA ; Harvard Stem Cell Institute, Holyoke Center, Suite 727W, 1350 Massachusetts Avenue, Cambridge, MA 02138, USA.
Abstract:
Cellular reprogramming was recently "crowned" with the award of the Nobel Prize to two of its groundbreaking researchers, Sir John Gurdon and Shinya Yamanaka. The recent link between reprogramming and stem cells makes this appear almost a new field of research, but its historical roots have actually spanned more than a century. Here, the Nobel Prize in Physiology or Medicine 2012 is placed in its historical context.
Related Concept Videos
Introduction to Nuclear Reprogramming
Methods of Nuclear Reprogramming
Somatic to iPS Cell Reprogramming
Exon Recombination
Exon shuffling follows “splice frame rules.” Each exon has three reading...
Induced Pluripotent Stem Cells
Somatic cells are...
Induced Pluripotent Stem Cells

