Related Experiment Video
Updated: May 7, 2026

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
Published on: April 25, 2014
IS6110-based differentiation of Mycobacterium tuberculosis strains
Anna Zaczek1, Małgorzata Ziółkiewicz, Arkadiusz Wojtasik
1Department of Biochemistry and Cell Biology, Faculty of Biology and Agriculture, University of Rzeszów, Cwiklińskiej 2, 35-601 Rzeszów, Poland.
Abstract:
In this study, 62 Mycobacterium tuberculosis strains were characterized by fast ligation-mediated PCR (FLiP) and, previously performed, IS6110 restriction fragment length polymorphism (RFLP). FLiP proved a reproducible and specific method for differentiation between M. tuberculosis strains. The discriminatory power of FLiP was close to that of the reference IS6110 RFLP suggesting its usefulness in studying the genetic diversity of M. tuberculosis strains.
