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Updated: May 7, 2026

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
Published on: June 3, 2021
Cerebral venous circulatory system evaluation by ultrasonography
Iris Zavoreo1, Vanja Basić-Kes, Lucija Zadro-Matovina
1University Department of Neurology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia. iris_zavoreo@yahoo.com
This study explores ultrasound
Area of Science:
- Vascular anatomy and physiology
- Neuroimaging techniques
- Neurology
Background:
- The venous system, comprising pulmonary veins, systemic veins, and cranial venous sinuses, plays a crucial role in waste removal.
- Veins, characterized by thinner walls and larger lumens than arteries, accommodate 60-70% of total blood volume.
- Venous function is influenced by respiration, venous tone, cardiac function, gravity, and muscle pump activity.
Purpose of the Study:
- To demonstrate the utility of intracranial and extracranial ultrasound for evaluating head and neck venous circulation.
- To investigate chronic cerebrospinal venous insufficiency (CCVI) as a potential factor in neurodegenerative diseases.
Main Methods:
- Selective venography
- Doppler sonography
- Computed Tomography (CT) venography
- Magnetic Resonance (MR) venography
- Specialized extracranial and transcranial Doppler sonography for cerebral venous system evaluation.
Main Results:
- Ultrasound offers a viable method for assessing intracranial and extracranial venous flow.
- CCVI can be evaluated using these ultrasound techniques.
- The study highlights the potential link between venous insufficiency and neurodegeneration.
Conclusions:
- Intracranial and extracranial ultrasound provide valuable insights into head and neck venous circulation.
- Ultrasound can aid in the diagnosis and understanding of chronic cerebrospinal venous insufficiency.
- Further research is warranted to explore the role of venous insufficiency in neurodegenerative processes.
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