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Published on: November 4, 2010
Risk factors associated with poor controlled pediatric asthma in a university hospital
Ratchadaporn Papwijitsil1, Punchama Pacharn, Nichanun Areegarnlert
1Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Insights
In children, moderate to severe persistent asthma and sinusitis are linked to uncontrolled asthma. Air conditioner use may reduce the risk of poorly controlled asthma in pediatric patients.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
Background:
- Asthma control factors are well-established in adults but less defined in children.
- Identifying pediatric-specific asthma control determinants is crucial for effective management.
Purpose of the Study:
- To investigate the risk factors associated with partly or uncontrolled asthma in a pediatric population.
- To identify factors influencing asthma control levels in children.
Main Methods:
- Recruited pediatric patients with at least mild persistent asthma.
- Classified asthma control using the Global Initiative for Asthma (GINA) guidelines.
- Compared risk factors between controlled and partly controlled/uncontrolled asthma groups.
Main Results:
- Moderate/severe persistent asthma (adjusted OR 18.87) and sinusitis (p=0.04) were significant risk factors for uncontrolled asthma.
- Air conditioner use was associated with a decreased risk of uncontrolled asthma (adjusted OR 0.30).
- Higher use of medium-dose inhaled corticosteroid (ICS) plus long-acting inhaled β2-agonist (LABA) was observed in the partly controlled/uncontrolled group (p=0.004).
Conclusions:
- Moderate/severe persistent asthma and sinusitis are key risk factors for poor asthma control in children.
- Air conditioner usage appears to be a protective factor against uncontrolled asthma in this age group.
Background:
Many studies in adults had identified factors associated with partly or uncontrolled asthma. In children, factors related to asthma control were not well defined.
Objective:
To find the factors related to partly or uncontrolled asthma in children.
Methods:
Asthmatic children who had severity at least in the mild persistent level, were recruited. The asthma control levels were classified as controlled, partly controlled and uncontrolled according to the GINA guideline. Risk factors were compared between the patients with controlled and partly controlled/ uncontrolled asthma groups.
Results:
One hundred and ten patients (42.7% females) were included. The mean age was 10.3 ± 2.7 years old. There were 55 patients (50%) in the controlled, 54 patients(49.1%) in partly controlled and 1 patient (0.9%) in uncontrolled asthma group. For asthma severity, 97 patients (88.2%) were in mild persistent, 11 patients (10%) in moderate persistent and 2 patients (1.8%) in severe persistent groups. The risk factors for partly controlled/ uncontrolled asthma compared to controlled asthma were moderate/ severe persistent asthma (adjusted OR 18.87 (95% CI 1.92 - 200.00)) and sinusitis (p = 0.04). Using the air conditioner decreased risk of partly controlled/uncontrolled asthma (adjusted OR 0.30 (95% CI 0.10 - 0.91)). The proportion of patients who used medium dose inhaled corticosteroid (ICS) plus long-acting inhaled β2-agonist (LABA) were significantly higher in partly controlled/ uncontrolled asthma than controlled asthma (p = 0.004).
Conclusion:
Risk factors associated with partly controlled/ uncontrolled asthma were moderate/ severe persistent asthma and sinusitis. Using air conditioner seemed to reduce risk of partly controlled/ uncontrolled asthma.
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