Risk factors associated with poor controlled pediatric asthma in a university hospital

Ratchadaporn Papwijitsil1, Punchama Pacharn, Nichanun Areegarnlert

  • 1Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Insights

In children, moderate to severe persistent asthma and sinusitis are linked to uncontrolled asthma. Air conditioner use may reduce the risk of poorly controlled asthma in pediatric patients.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology

Background:

  • Asthma control factors are well-established in adults but less defined in children.
  • Identifying pediatric-specific asthma control determinants is crucial for effective management.

Purpose of the Study:

  • To investigate the risk factors associated with partly or uncontrolled asthma in a pediatric population.
  • To identify factors influencing asthma control levels in children.

Main Methods:

  • Recruited pediatric patients with at least mild persistent asthma.
  • Classified asthma control using the Global Initiative for Asthma (GINA) guidelines.
  • Compared risk factors between controlled and partly controlled/uncontrolled asthma groups.

Main Results:

  • Moderate/severe persistent asthma (adjusted OR 18.87) and sinusitis (p=0.04) were significant risk factors for uncontrolled asthma.
  • Air conditioner use was associated with a decreased risk of uncontrolled asthma (adjusted OR 0.30).
  • Higher use of medium-dose inhaled corticosteroid (ICS) plus long-acting inhaled β2-agonist (LABA) was observed in the partly controlled/uncontrolled group (p=0.004).

Conclusions:

  • Moderate/severe persistent asthma and sinusitis are key risk factors for poor asthma control in children.
  • Air conditioner usage appears to be a protective factor against uncontrolled asthma in this age group.
Abstract

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