Related Experiment Video
Updated: May 7, 2026

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
Published on: January 30, 2020
SOPs and the right hospitals to improve outcome after cardiac arrest
1Department of Anaesthesiology, Division of Emergencies and Critical Care, Oslo University Hospital Ulleval, Kirkeveien 166, 0407 Oslo, Norway.
Insights
Improving survival after out-of-hospital cardiac arrest (OHCA) requires enhancing the entire Chain of Survival (COS). This review focuses on optimizing post-resuscitation care to improve survival rates and neurological outcomes.
Area of Science:
- Emergency Medicine
- Cardiology
- Critical Care Medicine
Background:
- Out-of-hospital cardiac arrest (OHCA) affects approximately 400,000 Europeans annually.
- Survival rates after OHCA remain suboptimal globally, despite advancements in cardiopulmonary resuscitation (CPR) guidelines.
- Significant geographical variations in OHCA survival highlight the potential for improvement.
Purpose of the Study:
- To review the critical role of post-resuscitation care in the Chain of Survival (COS) for OHCA.
- To identify key elements of high-quality hospital treatment following return of spontaneous circulation (ROSC).
- To explore how improved post-resuscitation care impacts both survival rates and neurological outcomes.
Main Methods:
- This is a review article, synthesizing existing evidence on post-resuscitation care.
- The focus is on the final link in the Chain of Survival: hospital management after ROSC.
- Analysis of factors contributing to survival disparities and the impact of care quality.
Main Results:
- Survival rates after OHCA vary widely across different regions.
- The quality of the local Chain of Survival (COS), particularly post-resuscitation care, is a major determinant of survival.
- Optimizing hospital treatment after ROSC is crucial for improving patient outcomes.
Conclusions:
- Enhancing the quality of post-resuscitation care is essential for increasing OHCA survival.
- Effective post-resuscitation strategies can significantly improve survival with intact neurological function.
- Targeting and improving weak links in the COS, especially the hospital phase, offers a pathway to better patient outcomes.
Abstract:
Approximately 400,000 Europeans are yearly resuscitated from out-of-hospital cardiac arrest (OHCA).(1,2) Despite evolving evidence based guidelines for cardiopulmonary resuscitation (CPR), survival rates after OHCA has not improved much in several places around the world. However, a potential for improved survival is absolutely present, based on the huge spread in worldwide survival; some cities with survival over 20-30% and some cities with just a few percent.(1,2) These survival differences can partly be explained by different definitions of OHCA,(2) but mainly due to the overall quality of the local Chain of Survival (COS)(3); early arrest recognition and call for help, early CPR, early defibrillation and early post resuscitation care. By identifying and thereafter improving weak links in the local COS, survival can indeed increase. This review will focus on the quality of the last link in the COS, the hospital treatment after return of spontaneuous circulation (ROSC), and how good quality post resuscitation care can improve not only survival, but survival with neurologically intact outcome.
More Related Videos
08:19Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs
Published on: July 12, 2022
03:13Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
Related Concept Videos
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiopulmonary Resuscitation I: Adult
Acute Coronary Syndrome IV: Interprofessional Care
Cardiopulmonary Resuscitation III: AED Use
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Acute Coronary Syndrome V: Nursing Management