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First steps for integrating sex and gender considerations into basic experimental biomedical research
Stacey A Ritz1, David M Antle, Julie Côté
11Northern Ontario School of Medicine, East Campus-Laurentian University, 935 Ramsey Lake Rd., Sudbury, ON P3E 2C6, Canada. sritz@nosm.ca.
Summary
Basic biomedical researchers face challenges incorporating sex and gender into studies. This work outlines these issues and proposes feasible strategies for integrating sex and gender considerations in cell culture and animal research.
Area of Science:
- Basic biomedical research
- Sex and gender in medicine
Background:
- Growing recognition of the need to include sex and gender in biology and medicine.
- Existing research often exhibits a masculine bias, leading to knowledge gaps.
- Challenges in incorporating sex and gender in basic research are not well-articulated.
Purpose of the Study:
- To describe specific challenges faced by basic experimental biomedical researchers in incorporating sex and gender considerations.
- To propose feasible strategies for integrating sex and gender into research involving cell cultures and laboratory animals.
Main Methods:
- Qualitative analysis of challenges encountered in basic experimental research.
- Literature review on sex and gender in biomedical research.
- Development of practical strategies for researchers.
Main Results:
- Identified unique, unaddressed challenges in applying sex and gender considerations in cell culture and animal models.
- Proposed strategies that enable meaningful integration without compromising scientific inquiry.
Conclusions:
- Addressing sex and gender in basic research requires practical, feasible strategies.
- Mainstreaming these considerations is crucial for a comprehensive understanding of biology and medicine.
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