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Congenital eventration of the diaphragm - 45 years' perspective

K Vanamo1, R Rintala, H Lindahl

  • 1Children's Hospital, University of Helsinki, SF-00290, Helsinki, Finland.

Pediatric Surgery International
|September 24, 2013
PubMed

Insights

Congenital eventration of the diaphragm in children was studied over 45 years. Later cases presented earlier with acute symptoms, and mortality rates varied significantly across different treatment periods.

Area of Science:

  • Pediatric Surgery
  • Thoracic Surgery
  • Congenital Diaphragmatic Abnormalities

Background:

  • Congenital eventration of the diaphragm is a rare condition affecting infants.
  • Surgical management has evolved over decades, necessitating analysis of long-term outcomes.

Purpose of the Study:

  • To analyze surgical outcomes for congenital eventration of the diaphragm in children.
  • To identify trends in presentation and mortality over a 45-year period.

Main Methods:

  • Retrospective chart review of 55 pediatric patients operated for congenital eventration of the diaphragm.
  • Study divided into three 15-year periods (1948-1962, 1963-1977, 1978-1992).
  • Analysis of patient presentation, associated anomalies, and mortality rates.

Main Results:

  • Later patient cohorts presented with earlier onset and more severe symptoms.
  • Mortality rates were 14% (1948-1962), 27% (1963-1977), and 7% (1978-1992).
  • Mortality was strongly associated with pulmonary hypoplasia and chromosomal defects.

Conclusions:

  • Surgical outcomes for congenital eventration of the diaphragm have improved over time.
  • Early diagnosis and management of associated anomalies are crucial for reducing mortality.
  • Further research into the genetic and developmental factors is warranted.

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