Related Experiment Video

Updated: May 7, 2026

Intracranial Cannula Implantation for Serial Locoregional Chimeric Antigen Receptor (CAR) T Cell Infusions in Mice
05:22

Intracranial Cannula Implantation for Serial Locoregional Chimeric Antigen Receptor (CAR) T Cell Infusions in Mice

Published on: February 24, 2023

Carcinoma of the rectum in children

S P Sahoo1, A N Gangopadhyay, D K Gupta

  • 1Division of Paediatric Surgery, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India.

Pediatric Surgery International
|September 24, 2013
PubMed

Insights

Pediatric rectal carcinoma is rare, presenting as acute intestinal obstruction in children. These cases highlight the unique, poorer prognosis and distinct characteristics of childhood colorectal cancer compared to adults.

Area of Science:

  • Pediatric Oncology
  • Gastrointestinal Surgery
  • Colorectal Cancer Research

Background:

  • Colorectal carcinoma is exceptionally rare in pediatric populations.
  • Childhood colorectal cancer exhibits distinct clinical, pathological, and biological features compared to adult-onset disease.
  • Early presentation in children often involves acute intestinal obstruction, differing from typical adult symptoms.

Purpose of the Study:

  • To present two pediatric cases of rectal carcinoma.
  • To discuss the unique presentation, characteristics, and poorer prognosis of colorectal cancer in children.
  • To briefly outline management strategies for pediatric rectal carcinoma.

Main Methods:

  • Case report methodology detailing two pediatric patients diagnosed with rectal carcinoma.
  • Clinical data review including patient history, symptoms, and diagnostic findings.
  • Literature review on pediatric colorectal cancer characteristics and outcomes.

Main Results:

  • Two cases of rectal carcinoma in children aged 10 and 11 years are described.
  • Both patients presented with acute intestinal obstruction, rectal bleeding, constipation, abdominal distention, and weight loss.
  • The study underscores the rarity and aggressive nature of colorectal cancer in pediatric patients.

Conclusions:

  • Rectal carcinoma in children is a rare but serious condition with distinct features from adult cases.
  • The prognosis for pediatric colorectal cancer is generally poorer than in adults, necessitating specialized management approaches.
  • Prompt recognition and tailored treatment are crucial for improving outcomes in childhood rectal cancer.

More Related Videos

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.505:45

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

Published on: April 26, 2019

Related Concept Videos

The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...