Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Electrochemical Cells

Electrochemical Cells

Electrochemical cells are systems that convert chemical energy into electrical energy or use electrical energy to drive chemical reactions. They consist of two electrodes in contact with an electrolyte, where redox reactions enable electron transfer. Most electrochemical cells include two half-cells connected by an external wire for electron flow and a salt bridge for ion flow. The salt bridge contains an electrolyte solution and maintains charge neutrality by allowing ions—not electrons—to...

Voltaic/Galvanic Cells

Voltaic/Galvanic Cells

Spontaneous Chemical Reactions
Spontaneous redox reactions occur abundantly in nature. The chemical reaction occurring in a disposable AA battery powering our remote controls is one such example of a spontaneous redox reaction. Another example is the immersion of coiled copper wire into an aqueous silver nitrate solution. The reaction shows a gradual, visually impressive color change from colorless to bright blue and the formation of a grey precipitate on the copper wire. In this experiment,...

Concentration Cells

Concentration Cells

A concentration cell is an electrochemical cell in which the emf arises from a difference in concentration of a species between two half-cells. Unlike galvanic cells, where electrical energy comes from a chemical reaction, the driving force here is the transfer of matter from a region of higher concentration to lower concentration. The overall process is therefore physical in nature. A classic illustration is a cell made of two chlorine electrodes operating at different chlorine gas...

Concentration Cells

Concentration Cells

A concentration cell is a type of a voltaic cell constructed by connecting two almost identical half-cells, both based on the same half-reaction and using the same electrode, differing only in the concentration of one redox species. A concentration cell's potential, therefore, is determined only by the concentration difference of the particular redox species.
Consider the following voltaic cell:

Controlled-Current Coulometry: Coulometric Titration

Controlled-Current Coulometry: Coulometric Titration

Coulometric titrations are a form of titrimetric analysis where the reagent is generated electrically, and its amount is evaluated based on current and generating time. The electron serves as the standard reagent. The procedure is similar to conventional titrations, such as endpoint detection.
The fundamental requirements for coulometric titrations are (1) 100% efficiency in the reagent-generating electrode reaction and (2) a stoichiometric and preferably rapid reaction between the generated...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Characterization of solute distribution following iontophoresis from a micropipet.

Analytical chemistry·2014

Same author

Submicroliter electrochemistry and spectroelectrochemistry using standard electrodes and a polymer electrolyte salt bridge.

Analytical chemistry·2013

Same author

Easily constructed spectroelectrochemical cell for batch and flow injection analyses.

Analytical chemistry·2002

See all related articles

Search research articles

Related Experiment Video

Updated: May 7, 2026

Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy

Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy

Published on: May 12, 2023

Easily Constructed Microscale Spectroelectrochemical Cell.

Paul A Flowers¹, Jordan C Strickland

¹Chemistry and Physics Department, The University of North Carolina at Pembroke, Pembroke, North Carolina, USA.

Spectroscopy Letters; an International Journal for Rapid Communication

|September 24, 2013

Summary

A new microscale spectroelectrochemistry cell using Nafion as a salt bridge enables sensitive analysis of small liquid samples. This easily constructed design allows for visible absorption measurements and rapid electrolysis of microliter volumes.

Keywords:

electrochemical cell microscale analysis spectroelectrochemistry

More Related Videos

Using Cyclic Voltammetry, UV-Vis-NIR, and EPR Spectroelectrochemistry to Analyze Organic Compounds

Using Cyclic Voltammetry, UV-Vis-NIR, and EPR Spectroelectrochemistry to Analyze Organic Compounds

Published on: October 18, 2018

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Published on: July 24, 2018

Related Experiment Videos

Last Updated: May 7, 2026

Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy

Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy

Published on: May 12, 2023

Using Cyclic Voltammetry, UV-Vis-NIR, and EPR Spectroelectrochemistry to Analyze Organic Compounds

Using Cyclic Voltammetry, UV-Vis-NIR, and EPR Spectroelectrochemistry to Analyze Organic Compounds

Published on: October 18, 2018

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Published on: July 24, 2018

Area of Science:

Analytical Chemistry
Electrochemistry
Spectroscopy

Background:

Microscale analytical techniques are crucial for efficient sample analysis.
Spectroelectrochemistry combines spectroscopic and electrochemical methods for detailed molecular studies.
Existing microscale cells can be complex to construct and operate.

Purpose of the Study:

To design and evaluate a simple, cost-effective cell for microscale spectroelectrochemical analysis.
To demonstrate the cell's capability for sensitive measurements and rapid electrolysis.
To explore potential modifications for enhanced analytical performance.

Main Methods:

Construction of a microscale cell utilizing a Nafion polymer film as a salt bridge.
Integration of a coiled wire working electrode within a small sample well.
Separation of reference and auxiliary electrodes in larger wells.
Performance evaluation using aqueous ferri/ferrocyanide as a test system.

Main Results:

The cell successfully facilitated ionic contact for spectroelectrochemical measurements.
Sensitive visible absorption measurements were achieved with millimeter path lengths.
Bulk electrolysis of 1-5 μL samples was accomplished in approximately 5 minutes.
The design proved capable of handling small sample volumes efficiently.

Conclusions:

The developed microscale spectroelectrochemistry cell is effective for analyzing small sample volumes.
The use of Nafion as a salt bridge simplifies cell construction and operation.
The cell design shows promise for adaptation to sub-microliter volumes, multi-sample analysis, and UV spectral measurements.