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Updated: May 7, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
A case of ophthalmoplegic migraine: some observations
1Kolkata Institute of Neurosciences; Kolkata, India - drsatyanpatro@gmail.com.
Abstract:
We describe a 43-year-old man with a long-standing history of headache and ophthalmoplegia. Brain MRI showed a nodular enhancing lesion at the root exit zone of the left oculomotor nerve. Contrast enhancement on follow-up MRI and clinical symptoms showed a partial resolution on starting prophylactic anti-migraine medications. This was confirmed to be a case of ophthalmoplegic migraine. Here we describe a rare case of OM in an adult patient with its characteristic imaging pattern and the differential diagnosis considered.
Insights
Ophthalmoplegic migraine (OM) is a rare disorder characterized by recurrent episodes of headache and temporary paralysis of eye muscles. This case highlights a rare adult presentation of OM with characteristic MRI findings and successful management with migraine prophylaxis.
Area of Science:
- Neurology
- Neuro-ophthalmology
- Radiology
Background:
- Ophthalmoplegic migraine (OM) is a rare neurological disorder characterized by recurrent episodes of headache associated with ophthalmoplegia.
- While typically seen in children, adult-onset OM presents unique diagnostic challenges.
Purpose of the Study:
- To describe a rare case of adult-onset ophthalmoplegic migraine.
- To illustrate the characteristic neuroimaging findings of OM.
- To discuss the differential diagnosis for this condition.
Main Methods:
- Case report of a 43-year-old male with chronic headache and ophthalmoplegia.
- Brain MRI with contrast to evaluate the lesion.
- Clinical follow-up and response to prophylactic anti-migraine medication.
Main Results:
- Brain MRI revealed a nodular enhancing lesion at the root exit zone of the left oculomotor nerve.
- The patient experienced partial symptom resolution with prophylactic anti-migraine treatment.
- Diagnosis of ophthalmoplegic migraine was confirmed.
Conclusions:
- Ophthalmoplegic migraine can occur in adults, presenting with distinct imaging features.
- Prophylactic anti-migraine medications can be effective in managing adult OM.
- Characteristic MRI findings aid in differentiating OM from other causes of headache and ophthalmoplegia.
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