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Related Concept Videos

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
False Memories01:18

False Memories

False memories represent a cognitive distortion in which individuals recall events that did not happen, or remember them in an altered form. This phenomenon highlights the brain's constructive nature in processing and recalling memories, emphasizing that memory is not a perfect representation of past events but rather a dynamic reconstruction influenced by various factors.
One primary source of false memories is misattribution, where individuals incorrectly associate external information with...
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or playing an...
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...

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Related Experiment Video

Updated: May 7, 2026

Generalized Psychophysiological Interaction (PPI) Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
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Published on: November 14, 2017

Age differences in hippocampus-cortex connectivity during true and false memory retrieval.

Pedro M Paz-Alonso1, Pamela Gallego, Simona Ghetti

  • 11 Basque Center on Cognition, Brain and Language (BCBL), Donostia-San Sebastián, Gipuzkoa, Spain.

Journal of the International Neuropsychological Society : JINS
|September 25, 2013
PubMed
Summary
This summary is machine-generated.

Adults and children show different brain activity patterns during true and false memory retrieval. Functional connectivity reveals distinct neural networks supporting accurate recall versus susceptibility to false memories based on age.

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The Deese-Roediger-McDermott (DRM) Task: A Simple Cognitive Paradigm to Investigate False Memories in the Laboratory
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Last Updated: May 7, 2026

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The Deese-Roediger-McDermott (DRM) Task: A Simple Cognitive Paradigm to Investigate False Memories in the Laboratory
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The Deese-Roediger-McDermott (DRM) Task: A Simple Cognitive Paradigm to Investigate False Memories in the Laboratory

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14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Developmental Psychology

Background:

  • True and false memory retrieval involve distinct neural processes.
  • Developmental changes in memory retrieval are not fully understood.
  • The Deese/Roediger-McDermott (DRM) paradigm is a robust tool for studying false memories.

Purpose of the Study:

  • To investigate age-related differences in functional brain connectivity during true and false memory retrieval.
  • To examine how semantic association strength influences memory retrieval networks in children and adults.
  • To elucidate the role of the anterior hippocampus in memory accuracy and susceptibility to false memories.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was used to measure brain activity.
  • Participants (8-9 year olds and adults) completed the DRM paradigm with varying semantic association strengths.
  • Functional connectivity analysis assessed brain region coupling during true and false recognition tasks.

Main Results:

  • Adults showed higher true and false recognition than children.
  • True recognition involved hippocampal-temporal and fronto-parietal coupling.
  • False recognition engaged more distributed fronto-parietal-temporal networks.
  • Adults had stronger hippocampal/parietal and hippocampal/dorsolateral PFC coupling for true memories.
  • Children exhibited stronger hippocampus/ventrolateral PFC and temporal gyrus/ventrolateral PFC coupling for false memories.

Conclusions:

  • Age significantly modulates functional connectivity patterns during memory retrieval.
  • Distinct neural networks support true versus false memory, with age-specific differences.
  • The anterior hippocampus plays a crucial role in both accurate and false memory, with age-dependent functional engagement.