Central motor conduction in ischaemic and hemorrhagic cerebral lesions

Electrical Transcranial Cortical Stimulation was performed in 20 healthy volunteers and 14 patients having supra- or infratentorial vascular lesions. Central Conduction Time (CCT) in the Pyramidal Tract (PT) was calculated by subtraction of the Peripheral Conduction Time and the spinal synaptic delay to the Motor Evoked Potential (MEP) latency. Twelve out of fourteen patients showed prolonged MEP latencies or CCTs in the affected corporal segments. Only in 3 cases, 2 with subcortical hematoma and other with bilateral ischaemic lesions, the PT was inexcitable. Two patients, one with a discrete cortical lesion and the other with an hemispheric cerebellar infarct showed no abnormalities in pyramidal conduction. Electrophysiological results showed a good correspondence with the degree of clinical impairment.