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Updated: May 7, 2026

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Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model
Published on: February 10, 2023
Intra-pericardial thrombin injection for post-infarction left ventricular free wall rupture
Joe-Kin-Tong Lee1, Kin-Lam Tsui, Kwok-Keung Chan
1Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Hong Kong Special Administrative Region, China.
European Heart Journal. Acute Cardiovascular Care
|September 25, 2013
Abstract:
Left ventricular free wall rupture (LVFWR) is a fatal complication of acute myocardial infarction. Different modalities of treatment were previously described, including surgical intervention and medical treatment. We report a case treated with intra-pericardial thrombin injection that gave a favourable outcome for a patient who presented with LVFWR and cardiac tamponade, following acute myocardial infarction.

