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Syphilitic uveitis in a Singaporean population
Sae Cheong Yap1, Yar Li Tan, Martin T W Chio
1Yong Loo Lin School of Medicine, National University of Singapore , Singapore .
Ocular Immunology and Inflammation
|September 26, 2013
Summary
Ocular syphilis, a global resurgence, presents with diverse uveitis forms, most commonly anterior uveitis and panuveitis. Prompt penicillin treatment effectively manages this vision-threatening condition.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Public Health
Background:
- Ocular syphilis is experiencing a global resurgence, posing a significant threat to vision.
- Understanding the varied clinical presentations of syphilitic uveitis is crucial for timely diagnosis and treatment.
Purpose of the Study:
- To describe the clinical presentations of syphilitic uveitis in Singapore.
- To highlight the spectrum of ocular manifestations associated with syphilis.
Main Methods:
- Retrospective, noncomparative observational case series.
- Involved 12 patients (18 eyes) diagnosed with ocular syphilis between 2004 and 2009.
Main Results:
- The most common presenting complaint was blurred vision (61.1%).
- Anterior uveitis and panuveitis were the most frequent types (33.3% each).
- Serological tests for syphilis were highly positive (100% treponemal, 83.3% nontreponemal).
Conclusions:
- Syphilitic uveitis presents with a wide range of ocular findings.
- Despite potential for severe vision loss, effective treatment with penicillin is available.
- Early diagnosis and treatment are essential to prevent vision impairment.
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