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Updated: May 7, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
[Hyponatraemia as the cause of severe cerebral symptoms]
David P Sonne1, Christian Overgaard-Steensen
1Medicinsk Afdeling F, Gentofte Hospital, Niels Andersens Vej 65, 2900 Hellerup. dpsonne@gmail.com
Abstract:
Hyponatraemia with severe symptoms is a medical emergency that warrants swift action. Treatment can be delayed and/or insufficient if a systematic approach fails. We present two cases of severe symptomatic hyponatraemia: 1) Seizures treated with antiepileptics and isotonic saline, which fails to increase the plasma [Na+]/reveal the symptoms and 2) coma treated successfully with infusions of hypertonic saline boluses. Effective treatment is simple and involves management of airway, breathing and circulation together with bolus infusions of hypertonic saline to ensure controllable plasma [Na+] increase.
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