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Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
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Published on: August 31, 2013

Subcutaneous dirofilariasis.

A B Khyriem1, K G Lynrah, W V Lyngdoh

  • 1Department of Microbiology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.

Indian Journal of Medical Microbiology
|September 26, 2013
PubMed
Summary

Subcutaneous human dirofilariasis, a zoonotic infection caused by Dirofilaria repens, is uncommon in India. This case highlights the need to consider this parasitic infection in patients with subcutaneous nodules.

Area of Science:

  • Parasitology
  • Zoonotic Diseases
  • Medical Entomology

Background:

  • Subcutaneous human dirofilariasis is an uncommon zoonotic infection.
  • Dirofilaria repens is the causative agent.
  • Reports from India are limited but increasing globally.

Observation:

  • A case of subcutaneous dirofilariasis is reported.
  • The case originated from the state of Meghalaya, India.
  • The patient presented with subcutaneous nodules.

Findings:

  • Confirms the presence of Dirofilaria repens infection in a human.
  • Demonstrates a subcutaneous presentation of the zoonotic disease.
  • Adds to the limited case reports of human dirofilariasis in India.

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Implications:

  • Emphasizes the importance of considering dirofilariasis in differential diagnosis.
  • Highlights the need for increased awareness among clinicians in endemic and non-endemic areas.
  • Contributes to understanding the geographic distribution and clinical presentation of this zoonotic infection.