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The Tumor Microenvironment

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

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Related Experiment Video

Updated: May 7, 2026

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

Does "signet-ring stromal tumor" exist?

Teresa Pusiol¹, Doriana Morichetti, Maria Grazia Zorzi

¹Institute of Anatomic Pathology, Rovereto Hospital, Trento, Italy; teresa.pusiol@apss.tn.it.

Romanian Journal of Morphology and Embryology = Revue Roumaine De Morphologie Et Embryologie

|September 27, 2013

Summary

No abstract available in PubMed .

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