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Updated: May 7, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Response to comment on "Community-wide isoniazid preventive therapy drives drug-resistant tuberculosis: a model-based
Harriet L Mills1, Ted Cohen, Caroline Colijn
1Bristol Centre for Complexity Sciences, University of Bristol, Bristol BS8 1TR, UK.
Abstract:
Our modeling work suggests that isoniazid preventive therapy (IPT) can be effective in reducing drug-sensitive tuberculosis (TB) and that the risk of IPT driving resistance can be reduced by improving the detection and rapid treatment of individuals with drug-resistant disease and by limiting IPT to those in whom the intervention will have the largest benefit.
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