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Updated: May 7, 2026

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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Organ-specific regulatory T cells of thymic origin are expanded in murine prostate tumors
Sven Malchow1, Daniel S Leventhal, Peter A Savage
1Department of Pathology; University of Chicago; Chicago, IL USA.
Oncoimmunology
|September 28, 2013
Abstract:
Little is known about the relative contributions of self-specific regulatory T cells (Tregs) of thymic origin and induced Tregs generated extrathymically to the pool of tumor-infiltrating Tregs. We have recently demonstrated that thymic-derived Tregs reactive to a prostate-associated self antigen are highly and recurrently enriched within oncogene-driven murine prostate cancers.
