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Updated: May 7, 2026

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
Published on: June 18, 2018
A systematic review comparing cognitive-behavioral therapy and contingency management for cocaine dependence
Nadine S Farronato1, Kenneth M Dürsteler-Macfarland, Gerhard A Wiesbeck
1a Psychiatric Hospital of the University of Basel , Division of Substance Use Disorders , Basel , Switzerland.
None:
The main objective of this review was to compare the effectiveness of cognitive-behavioral therapy and contingency management for cocaine dependence. Contingency management alone reliably reduced cocaine use during active treatment in all cited trials, whereas the positive effect of cognitive-behavioral therapy emerged after treatment in 3 of 5 trials. Synergistic effects of the combination of contingency management plus cognitive-behavioral therapy are shown in 2 trials, but another 3 trials found no additive effects. Positive, rapid, and enduring effects on cocaine use are reliably seen with contingency management interventions, whereas measurable effects of cognitive-behavioral therapy emerge after treatment and are not as reliable as effects with contingency management.
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