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Related Concept Videos

Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
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Dermis
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Dermoscopy of Lentiginous Melanomas and Equivocal Benign Pigmented Macules of the Scalp: A Case-Control Multicentric Study.

Dermatology (Basel, Switzerland)·2023
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Comparison of humans versus mobile phone-powered artificial intelligence for the diagnosis and management of pigmented skin cancer in secondary care: a multicentre, prospective, diagnostic, clinical trial.

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Prognosis for people with multiple primary melanomas compared with a single primary melanoma.

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The association of dermatologist demographic density with melanoma survival in New South Wales, Australia.

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Skin cancer excisions and histopathology outcomes when following a contemporary population-based cohort longitudinally with 3D total-body photography.

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Updated: May 7, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Published on: May 16, 2025

Evidence-based dermoscopy.

Scott W Menzies1

  • 1Sydney Melanoma Diagnostic Centre, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia; Discipline of Dermatology, Sydney Medical School, The University of Sydney, NSW 2006, Australia.

Dermatologic Clinics
|October 1, 2013
PubMed
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Sequential digital dermoscopy imaging (SDDI) significantly improves melanoma detection, especially for featureless cases. This advanced technique also reduces unnecessary excisions of benign skin lesions.

Keywords:
DermoscopyEvidenceMelanomaSequential digital dermoscopy imaging

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Area of Science:

  • Dermatology
  • Oncology
  • Medical Imaging

Background:

  • Dermoscopy enhances melanoma diagnosis over naked-eye examination.
  • Sequential digital dermoscopy imaging (SDDI) aids in detecting subtle melanomas.
  • Reducing benign lesion excisions is a clinical goal.

Purpose of the Study:

  • To evaluate the impact of SDDI on melanoma detection rates.
  • To assess SDDI's effectiveness in reducing benign lesion excisions.
  • To highlight SDDI's role in clinical practice for high-risk individuals.

Main Methods:

  • Meta-analyses and clinical trials were reviewed.
  • The diagnostic accuracy of dermoscopy and SDDI was compared.
  • Excision rates of benign melanocytic lesions were analyzed.

Main Results:

  • SDDI enables detection of dermoscopic featureless melanoma.
  • SDDI exclusively identified 34% to 61% of melanomas in high-risk patients.
  • SDDI combined with dermoscopy reduced benign lesion excisions.

Conclusions:

  • SDDI is a valuable tool for improving melanoma diagnosis.
  • SDDI significantly impacts clinical practice by enhancing melanoma detection.
  • SDDI contributes to reducing unnecessary surgical procedures for benign lesions.