Related Experiment Video
Updated: May 7, 2026

11:52
Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
Published on: February 9, 2017
Temporal relation discovery between events and temporal expressions identified in clinical narrative
Yao Cheng1, Peter Anick1, Pengyu Hong1
1Computer Science Department, Brandeis University, United States.
Journal of Biomedical Informatics
|October 1, 2013
Summary
This study introduces a novel method for automatically detecting temporal event relations in electronic medical records. This advance improves understanding of disease progression and treatment responses using machine learning and rule-based systems.
Area of Science:
- Natural Language Processing
- Clinical Informatics
- Machine Learning
Background:
- Electronic medical records (EMRs) contain valuable information on disease progression and treatment efficacy.
- Automatic detection of temporal relations between events in EMRs can enhance their utility.
- Accurate temporal understanding is crucial for clinical decision support.
Purpose of the Study:
- To develop and evaluate a methodology for automatically labeling temporal relations between events in clinical text.
- To improve the extraction of clinically relevant temporal information from electronic medical records.
- To leverage machine learning and rule-based approaches for enhanced temporal relation extraction.
Main Methods:
- A three-step methodology combining machine learning and deterministic rules was applied to an annotated corpus.
- An expanded training network was created using transitive closure over annotated data.
- A voting mechanism resolved contradictions between local predictions from a learned classifier.
Main Results:
- The methodology demonstrated effective labeling of temporal relations in electronic medical records.
- Both machine learning and rule-based components contributed to prediction accuracy.
- Conflict resolution strategies improved the overall consistency of temporal relation predictions.
Conclusions:
- The proposed method significantly enhances the automatic detection of temporal relations in clinical text.
- This approach holds promise for improving the analysis of disease progression and treatment outcomes.
- Further development can lead to more robust clinical informatics tools.
Related Concept Videos
Introduction To Survival Analysis
Survival analysis is a statistical method used to study time-to-event data, where the "event" might represent outcomes like death, disease relapse, system failure, or recovery. A unique feature of survival data is censoring, which occurs when the event of interest has not been observed for some individuals during the study period. This requires specialized techniques to handle incomplete data effectively.
The primary goal of survival analysis is to estimate survival time—the time until a...
The primary goal of survival analysis is to estimate survival time—the time until a...
Framing Effects
Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in different ways based on the...
Drug Concentration Versus Time Correlation
The plasma drug concentration-time curve is a crucial tool in pharmacokinetics, representing the drug's concentration in plasma at different time intervals post-administration. This curve illustrates the drug's journey from absorption into the systemic circulation, distribution to body tissues, and eventual elimination through excretion or biotransformation.
Two pivotal parameters are the minimum effective concentration (MEC) and the minimum toxic concentration (MTC). The MEC is the lowest drug...
Two pivotal parameters are the minimum effective concentration (MEC) and the minimum toxic concentration (MTC). The MEC is the lowest drug...
Autobiographical Memory
Autobiographical memory is a unique type of episodic memory that involves recollecting personal life experiences. It allows individuals to remember significant events from their past, creating a narrative of their lives. One interesting phenomenon related to autobiographical memory is the reminiscence bump. This effect refers to the tendency of adults to recall more events from their second and third decades of life — typically between ages 10 to 30 — than from other periods. This period is...
Assessing Body Temperature - Temporal Artery
Here is a stepwise guide to assessing the body temperature at the temporal artery using a temporal artery thermometer
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's forehead...
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's forehead...
Reason and Intuition
The human brain processes information for decision-making using one of two routes: an intuitive system and a rational system (Epstein, 1994; popularized by Kahneman, 2011 as System 1 and System 2, respectively). The intuitive system is quick, impulsive, and operates with minimal effort, relying on emotions or habits to provide cues for what to do next, while the rational system is logical, analytical, deliberate, and methodical. Research in neuropsychology suggests that the brain can only use...

