Related Experiment Video

Updated: May 7, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

Modulation of A2B adenosine receptor by 1-Benzyl-3-ketoindole derivatives

Sabrina Taliani1, Maria Letizia Trincavelli, Barbara Cosimelli

  • 1Dipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy.

European Journal of Medicinal Chemistry
|October 1, 2013
PubMed

Keywords:
1-Benzyl-3-ketoindole derivatives2-chloro-N(6)-(3-iodobenzyl)-adenosine-5′-N-methyluronamide3′,5′-cyclic adenosine monophosphate4-dimethylaminopyridineA(2B) adenosine receptorADAARCHOChinese hamster ovaryCl-IBMECADMAPDMEMDulbecco's Modified Eagle MediumG-protein coupled receptorsGPCR modulatorsGPCRsLigand–receptor interactionNegative modulatorsPositive modulatorsSEM[(125)I]4-aminobenzyl-5′-N-methylcarboxamidoadenosine[(125)I]AB-MECA[(3)H]5′-N-ethylcarboxamideadenosine[(3)H]8-cyclopentyl-1,3-dipropylxanthine[(3)H]DPCPX[(3)H]NECAadenosine deaminaseadenosine receptorcAMPstandard error of mean

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