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Updated: May 7, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Cyclometalated platinum(II) with ethynyl-linked azobenzene ligands: an original switching mode
Paul Savel1, Camille Latouche, Thierry Roisnel
1Institut des Sciences Chimiques de Rennes UMR 6226 CNRS-Université de Rennes 1, 35042, Rennes Cedex, France. jean-luc.fillaut@univ-rennes1.fr abdou.boucekkine@univ-rennes1.fr.
Abstract:
The photophysical properties of 6-phenyl-2,2'-bipyridyl platinum(ii) complexes bearing different σ-alkynyl-linked azobenzene ancillary ligands were investigated. These complexes exhibited strong, broad, structureless charge-transfer bands in the visible region, which were red-shifted when the electron-donating ability of the para substituent on the azo-acetylide ligand increased. When excited at the charge-transfer absorption band, the complexes exhibited weak green emission, which was assigned to a triplet metal-to-ligand charge transfer/interligand charge transfer emission ((3)MLCT/(3)L'LCT). The presence of an amino substituent in the azobenzene moiety opened the possibility of protonation, which led to the formation of an azonium based derivative and resulted in drastic perturbations of the molecular orbitals and photophysical properties of the Pt-acetylide complex. These studies are fully supported by DFT and TD-DFT calculations.
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