Multiple intraneural glomus tumors on a digital nerve: case report

Area of Science:

• Oncology
• Neurology
• Pathology

Background:

• Glomus tumors are typically benign soft-tissue neoplasms.
• Intraneural glomus tumors are exceptionally rare, with most reported cases involving solitary lesions.
• Digital nerve involvement presents unique diagnostic and management challenges.

Observation:

• A patient presented with a symptomatic finger swelling, initially suspected to be a digital nerve neuroma based on imaging.
• Surgical exploration revealed multiple glomus tumors along the digital nerve.
• Histopathological examination confirmed the diagnosis of multiple intraneural glomus tumors.

Findings:

• The successful surgical excision of multiple digital nerve glomus tumors led to complete symptom resolution.
• This case underscores the possibility of multiple intraneural glomus tumors, challenging the typical solitary presentation.
• The study details the biology and clinico-pathologic features of peripheral nerve-associated glomus tumors.

Implications:

• Clinicians should consider multiple glomus tumors in the differential diagnosis of digital nerve masses, even when imaging suggests other pathologies.
• Understanding the presentation of rare intraneural glomus tumors is crucial for accurate diagnosis and effective treatment.
• This case contributes to the literature on rare nerve tumors and informs clinical decision-making for complex cases.