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Published on: September 5, 2025
Endoscopic therapy for chronic pancreatitis
1Division of Gastroenterology and Hepatology, Geneva University Hospitals, Rue Gabrielle Perret Gentil 4, Geneva 1211, Switzerland.
Abstract:
Endoscopic therapy is recommended as the first-line therapy for painful chronic pancreatitis with an obstacle on the main pancreatic duct (MPD). The clinical response should be evaluated at 6 to 8 weeks. Calcified stones that obstruct the MPD are first treated by extracorporeal shockwave lithotripsy; dominant MPD strictures are optimally treated with a single, large, plastic stent that should be exchanged within 1 year even in asymptomatic patients. Pancreatic pseudocysts for which therapy is indicated and are within endoscopic reach should be treated by endoscopy.
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