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Updated: May 7, 2026
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Case series and literature review of multiple nodular sarcoidosis
Hira Shahzad1, Sameer Ur-Rehman, Kulsoom Fatima
1Section of Pulmonary and Critical Care Medicine, Department of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan. ali.zubairi@aku.edu.
Background:
Nodular lung disease is a rare presentation of sarcoidosis. Radiologically it can present as multiple pulmonary masses or solitary lung nodule.
Case Presentation:
We report three cases of nodular sarcoidosis in young females of Asian origin who had initially presented with dry cough and worsening dyspnea non-responsive to initially administered antibiotics. Pulmonary nodules were discovered upon radiographic imaging in all three cases which raised concern for the possibility of neoplastic processes. Subsequent biopsies revealed granulomatous inflammation indicative of sarcoidosis. All cases responded very well to systemic corticosteroids.
Conclusion:
Sarcoidosis may present as nodular infiltrates which alerts the treating physician to other neoplastic and infectious diseases of the lungs. Appropriate workup may reveal the true nature of this disease and hence, simplify treatment.
