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Updated: May 7, 2026
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Bronchial asthma with ABPA presenting as PTE
Chandrika Azad1, Kana R Jat, Purnima Aggarwal
1Department of Pediatrics, Government Medical College and Hospital, Chandigarh, India.
Summary
This case report details a rare pediatric instance of allergic bronchopulmonary aspergillosis (ABPA) and severe asthma leading to pulmonary embolism and cor pulmonale, a combination previously undocumented in children.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
- Critical Care Medicine
Background:
- Allergic bronchopulmonary aspergillosis (ABPA) is a rare complication of asthma in children.
- Persistent, poorly-controlled asthma can lead to cor pulmonale in adults, but this is seldom reported in pediatric cases.
Observation:
- This report presents a pediatric case involving asthma and ABPA.
- The patient developed pulmonary thromboembolism and cor pulmonale.
Findings:
- The co-occurrence of asthma, ABPA, pulmonary thromboembolism, and cor pulmonale is described.
- This specific clinical association has not been previously documented in the pediatric population.
Implications:
- Highlights the potential for severe, complex respiratory complications in pediatric asthma.
- Suggests the need for heightened awareness and diagnostic vigilance for ABPA and its sequelae in children with severe asthma.
- Underscores the importance of early and effective management of pediatric asthma to prevent advanced complications like cor pulmonale.
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