[Effect of immunostimulants on the intensity of vaccinal antirabies immunity]

Experiments in BALB/c and CBA mice demonstrated that among 5 immunopotentiators (RFf2, a complex of polyguacylic and polycytidylic acids (GC), glucosomuramyldipeptide, levamisole, and dsRNA) a significant immunostimulating effect on the intensity of rabies immunity to intracerebral challenge with street rabies virus was exerted by RFf2 interferon inductor or by a combination of inosiplex + + GC + vaccine. A correlation between the immunostimulating and protective (therapeutic) activity of the drugs was established.