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Related Concept Videos

Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Oogenesis01:22

Oogenesis

Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
Reproductive Cloning01:27

Reproductive Cloning

Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
Reproductive Cloning01:27

Reproductive Cloning

Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...

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Related Experiment Video

Updated: May 7, 2026

In Vitro Culture Strategy for Oocytes from Early Antral Follicle in Cattle
09:30

In Vitro Culture Strategy for Oocytes from Early Antral Follicle in Cattle

Published on: July 8, 2020

Programmes and prospects for ovotechnology.

Roger G Gosden1

  • 1Jamestowne Bookworks, 107 Paddock Lane, Williamsburg, VA 23188, USA.

Reproductive Biomedicine Online
|October 3, 2013
PubMed
Summary
This summary is machine-generated.

New research explores generating more oocytes, the crucial cells for reproduction and aging. This could revolutionize treatments for infertility and ovarian insufficiency by overcoming the limited natural supply.

Keywords:
germ cellin vitrooocyteovarystem celltransplantation

Related Experiment Videos

Last Updated: May 7, 2026

In Vitro Culture Strategy for Oocytes from Early Antral Follicle in Cattle
09:30

In Vitro Culture Strategy for Oocytes from Early Antral Follicle in Cattle

Published on: July 8, 2020

Area of Science:

  • Reproductive Biology
  • Cellular Biology
  • Regenerative Medicine

Background:

  • Oocytes are vital for reproduction, aging, and disease, yet are rare in adults.
  • Current understanding suggests oogenesis halts after birth, leading to a finite follicle pool.
  • Follicle loss through atresia, rather than ovulation, depletes this store by menopause.

Purpose of the Study:

  • To review prospects for novel technologies to increase oocyte availability.
  • To challenge the established dogma of a finite oocyte reserve.
  • To explore methods for overcoming oocyte shortage for therapeutic applications.

Main Methods:

  • Review of existing literature on oogenesis and stem cell biology.
  • Exploration of potential biotechnological approaches for oocyte generation.
  • Analysis of the implications of persistent or inducible germline stem cells.

Main Results:

  • The traditional view of a finite oocyte supply may be incomplete.
  • Germline stem cells might persist postnatally or be generated from other stem cell sources.
  • In-vitro techniques offer potential for increased oocyte yield from existing follicles.

Conclusions:

  • Generating new oocytes, potentially from persistent or induced stem cells, offers a new paradigm.
  • This approach could overcome the limitations of finite follicle stores.
  • Developing these technologies could transform in-vitro fertilization, egg donation, and regenerative medicine for ovarian insufficiency.