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Related Concept Videos

Storage01:23

Storage

A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze each...
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Related Experiment Video

Updated: May 7, 2026

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Functional interactions between large-scale networks during memory search.

James E Kragel1, Sean M Polyn2

  • 1Department of Psychology Neuroscience Graduate Program, Vanderbilt University, Nashville, TN 37240, USA.

Cerebral Cortex (New York, N.Y. : 1991)
|October 3, 2013
PubMed
Summary
This summary is machine-generated.

The dorsal attention network (DAN) is transiently engaged during memory recall, challenging its role in external tasks. Brain network interactions reveal a specialized posteromedial network crucial for episodic retrieval.

Keywords:
DMNepisodic memoryfMRIfree recallfunctional connectivity

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Generalized Psychophysiological Interaction (PPI) Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

Area of Science:

  • Neuroimaging
  • Cognitive Neuroscience
  • Systems Neuroscience

Background:

  • The default mode network (DMN) and dorsal attention network (DAN) are key brain networks involved in internal and external cognitive tasks, respectively.
  • These networks typically exhibit anticorrelated activity during demanding tasks and rest.
  • Understanding their dynamic interactions is crucial for deciphering cognitive processes.

Purpose of the Study:

  • To investigate the functional interactions between the DMN and DAN during a self-initiated memory search task (free recall).
  • To explore the dynamic reorganization of these large-scale brain networks during internally directed cognition.
  • To identify specific DMN subnetworks involved in episodic memory retrieval.

Main Methods:

  • Utilized independent component analysis (ICA) on functional magnetic resonance imaging (fMRI) data.
  • Analyzed brain network activity and functional coupling during a free-recall task.
  • Examined transient network engagement and shifts in functional connectivity.

Main Results:

  • The dorsal attention network (DAN) showed transient engagement preceding successful memory retrieval, contrary to expectations for an internally directed task.
  • Independent component analysis revealed a three-component fractionation of the default mode network (DMN).
  • A posteromedial network within the DMN increased engagement during memory search, while other DMN components were suppressed. Cooperative interactions were maintained between the posteromedial network, a frontoparietal control network, and a medial prefrontal network.
  • The DAN exhibited heterogeneous, task-dependent changes in functional coupling with different DMN subnetworks.

Conclusions:

  • The findings suggest a broader role for the dorsal attention network (DAN) beyond externally directed cognition, including involvement in internally driven memory search.
  • The posteromedial network plays a significant role in episodic retrieval.
  • Dynamic functional reorganization and interplay between the DMN and DAN are critical for successful memory recall.