Related Experiment Video
Updated: May 7, 2026

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
Systems factors in obstetric care: the role of daily obstetric volume
Jonathan M Snowden1, Blair G Darney, Yvonne W Cheng
1Departments of Obstetrics and Gynecology, Medical Informatics and Clinical Epidemiology, and Emergency Medicine, and the Center for Health Systems Effectiveness, Oregon Health and Science University, Portland, Oregon; and the Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, California.
Objective:
To evaluate whether relatively high-volume days are associated with measures of obstetric care in California hospitals.
Methods:
This is a population-based retrospective cohort study of linked data from birth certificates and antepartum and postpartum hospital discharge records for California births in 2006. Birth asphyxia and nulliparous, term, singleton, vertex cesarean delivery rates were analyzed as markers of quality of obstetric care. Rates were compared between hospital-specific relatively high-volume days (days when the number of births exceeded the 75th percentile of daily volume for that hospital) and low-volume or average-volume days. Analyses were stratified by weekend and weekday and overall hospital obstetric volume. Multivariable logistic regression was used to control for confounders.
Results:
On weekends, relatively high-volume days were significantly associated with an elevated risk of asphyxia (27 out of 10,000 compared with 17 out of 10,000; P=.013), whereas no association was present on weekdays (13 out of 10,000 on high-volume days and 15 out of 10,000 on low-volume or average-volume days; P=.182). The cesarean delivery rate among the nulliparous, term, singleton, vertex population was significantly lower on high-volume weekend days (22.0% compared with 23.6% on low-volume or average-volume weekend days; P=.009), whereas no association was present on weekdays (27.1% on high-volume days and 27.6% on low-volume or average-volume days; P=.092).
Conclusion:
Delivery on relatively high-volume weekend days is a risk factor for birth asphyxia in California. High-volume weekend days also are associated with a lower rate of cesarean delivery in nulliparous women with singleton, vertex presentation pregnancies at term.
Level Of Evidence:
: II.
Related Concept Videos
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Factors Affecting Drug Distribution: Organ Perfusion Rate
Perfusion rate-limited distribution relies on the...
Respiratory Volumes
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Cardiac Output and Stroke Volume
In an average resting adult male, the typical cardiac output averages...
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...

