Multiple hepatic inflammatory pseudotumours diagnosed after laparoscopic excisional biopsy

Area of Science:

• Hepatology
• Surgical Pathology
• Oncology

Background:

• Inflammatory pseudotumours (IPTs) are uncommon benign lesions that can affect any organ, with the liver being the second most frequently involved.
• Hepatic IPTs typically present as solitary masses, posing diagnostic challenges due to their potential to mimic malignant liver tumors.
• Accurate diagnosis often necessitates invasive procedures like biopsies for histological examination.

Purpose of the Study:

• To present a case of multiple hepatic inflammatory pseudotumours.
• To highlight the diagnostic challenges in differentiating these lesions from liver metastases.
• To illustrate the successful management and outcome of this rare condition.

Main Methods:

• A case report detailing a patient with multiple liver lesions.
• Initial diagnostic attempts included two inconclusive percutaneous biopsies.
• Definitive diagnosis was established via laparoscopic exploration with excisional biopsy and subsequent pathological evaluation.

Main Results:

• The patient presented with multiple hepatic lesions that clinically mimicked liver metastases.
• Percutaneous biopsies were non-diagnostic, underscoring the difficulty in differentiating IPTs.
• Laparoscopic excisional biopsy confirmed the diagnosis of multiple hepatic inflammatory pseudotumours.

Conclusions:

• Multiple hepatic inflammatory pseudotumours can present as lesions mimicking metastatic disease, complicating diagnosis.
• Surgical intervention and pathological examination are crucial for definitive diagnosis when less invasive methods fail.
• These benign lesions may resolve spontaneously without specific treatment after diagnosis.