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Published on: September 26, 2018
Identifiable hypertension: a new spectrum
1Icahn School of Medcine at Mount Sinai, Cardiovascular Center, New York, NY.
Insights
Hypertension is a growing spectrum of disorders, including common associations like diabetes and rare genetic causes. Effective management requires tailored strategies beyond standard treatments to prevent cardiovascular disease.
Area of Science:
- Cardiology
- Endocrinology
- Oncology
Background:
- Hypertension presents as a broad spectrum of disorders.
- Common associations include diabetes, while rare causes involve genetic factors and iatrogenic effects.
- Cancer therapies, such as anti-VEGF treatments, can induce hypertension.
Purpose of the Study:
- To highlight the expanding scope of identifiable hypertension.
- To emphasize the need for specialized diagnostic and management strategies.
- To underscore the importance of these strategies in cardiovascular disease prevention.
Main Methods:
- Review of current literature on diverse causes of hypertension.
- Analysis of diagnostic challenges in secondary and drug-induced hypertension.
- Evaluation of management protocols for specific hypertension subtypes.
Main Results:
- Identifiable hypertension encompasses common comorbidities and rare genetic/iatrogenic causes.
- Standard hypertension treatment is insufficient for many of these specific forms.
- Tailored approaches are crucial for optimal patient outcomes.
Conclusions:
- The definition of hypertension must broaden to include diverse etiologies.
- Personalized diagnostic and therapeutic strategies are essential.
- Proactive management of these specific hypertension types is key to reducing cardiovascular risk.
Abstract:
Identifiable hypertension now encompasses a large and growing spectrum of disorders from the most common associations (eg, diabetes), to rare genetic disorders and adverse reactions (eg, hypertension caused by anti- VEGF cancer therapy). Each of these disorders requires strategies for diagnosis and management that extend well beyond the usual treatment of hypertension for maximal benefit in preventing cardiovascular disease.
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