Related Experiment Video
Updated: May 7, 2026

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
Published on: January 31, 2022
Comparative efficacy of three forms of parenteral iron
Richard Dillon1, Ibrahim Momoh, Yvonne Francis
1Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK.
Abstract:
Intravenous iron therapy is a useful treatment for the rapid correction of iron deficiency anaemia and can be used to avoid or reduce the requirement for allogeneic blood transfusion. Several intravenous iron preparations are available commercially which differ in cost, mode of administration and side effect profile. There are few data directly comparing the efficacy of these preparations. In this retrospective single-centre study, we present the results from two hundred and eight patients treated using three different iron preparations (iron dextran, iron sucrose and ferric carboxymaltose) and compare the effect on haemoglobin levels and other measures of iron deficiency six weeks after treatment. Within the limitations of our study design, we show a statistically and clinically significant difference in efficacy between these preparations.
Related Concept Videos
Routes of Drug Administration: Parenteral
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
Drug Delivery: Parenteral Route
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence
Bioavailability Study Design: Absolute Versus Relative Bioavailability
Modified-Release Drug Delivery Systems: Bioavailability
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

