Related Experiment Video
Updated: May 7, 2026

A Model for Experimental Exposure of Humans to Larval Ixodes scapularis Ticks
Published on: December 1, 2023
[Update on SENLAT syndrome: scalp eschar and neck lymph adenopathy after a tick bite]
M Foissac1, C Socolovschi, D Raoult
1Aix Marseille université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, 13005 Marseille, France.
Abstract:
SENLAT syndrome, also known as TIBOLA/DEBONEL, is an emerging disease in France. The major symptoms are necrotic eschar on the scalp associated with painful cervical lymphadenopathy. It occurs mainly in women and children during the cold seasons after a bite by a Dermacentor tick, responsible for transmitting Rickettsia slovaca or Rickettsia raoultii. Cutaneous swabs are safe, easy and reliable tools that should be used routinely by physicians to confirm diagnosis. In this particular disease, they should be preferred to serology, which is less sensitive. Doxycycline is the antibiotic of choice for this syndrome.
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