Hypertension associated with coarctation of the aorta revisited: case-based update from experience of three children
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Published on: March 28, 2025
Ali Baykan1, Mustafa Argun, Abdullah Ozyurt
1Division of Pediatric Cardiology, Department of Pediatrics, Erciyes University Medical Faculty, Melikgazi, 38039 Kayseri, Turkey.
Insights
Coarctation of the aorta (CoA) can cause hypertension and stroke in children. Early diagnosis through physical examination is crucial for prompt treatment and preventing severe neurological complications.
Area of Science:
- Pediatric Cardiology
- Neurology
- Vascular Surgery
Background:
- Coarctation of the aorta (CoA) presents varied clinical manifestations based on severity and age.
- Delayed diagnosis and treatment of CoA can lead to severe neurological events like intracranial hemorrhage or infarction.
- Systemic hypertension is a significant clinical presentation of CoA, particularly in pediatric patients.
Purpose of the Study:
- To highlight Coarctation of the aorta as a potential cause of systemic hypertension in pediatric patients.
- To emphasize the distinct diagnostic approaches for hypertension in children compared to adults.
- To draw attention to CoA as a cause of stroke in adolescents.
Main Methods:
- Case report analysis of pediatric patients presenting with CoA and associated neurological events.
- Review of diagnostic strategies for hypertension in children.
- Emphasis on the role of physical examination in identifying potential CoA.
Main Results:
- Three cases are presented: two of hypertensive cerebral hemorrhage and one of hypertensive cerebellar infarction linked to CoA.
- These cases underscore the association between CoA and stroke in the adolescent population.
- The findings highlight the importance of considering CoA in the differential diagnosis of pediatric hypertension and stroke.
Conclusions:
- Coarctation of the aorta should be considered in adolescents presenting with hypertensive stroke.
- Physical examination is vital for evaluating hypertension in children.
- A specialized diagnostic approach is necessary for secondary hypertension in pediatric cases.
Abstract:
Coarctation of the aorta (CoA) can present with different clinical pictures depending on the severity of the narrowness in the coarcted aortic segment in an age range between newborn and adolescence. Sometimes, it can cause intracranial hemorrhage or infarction when diagnosis and treatment are delayed. The aim of this report is taking attention to CoA as a cause of systemic hypertension and is also emphasizing the differences of diagnostic approach for hypertension in children from adults. Two cases of hypertensive cerebral hemorrhage and one case of hypertensive cerebellar infarction associated with CoA are reported. These cases help us to pay attention to the possibility of CoA in adolescents with hypertensive stroke. We want to emphasize the importance of physical examination for evaluation of hypertension and to impress the diagnostic approach for secondary hypertension in children.
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