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Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...

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Related Experiment Video

Updated: May 7, 2026

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

Locking versus nonlocking construct in an osteoporotic, segmental fibula defect model.

Eddie Y Lo, Susan S Tseng, Blaine A Christiansen

    Orthopedics
    |October 8, 2013
    PubMed
    Summary
    This summary is machine-generated.

    For osteoporotic fibula fractures, locking plates did not improve construct stability compared to nonlocking plates in biomechanical testing. This study suggests nonlocking constructs may be sufficient for these challenging fracture types.

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    Published on: April 11, 2012

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    Last Updated: May 7, 2026

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    06:38

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    Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
    07:35

    Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

    Published on: April 11, 2012

    Area of Science:

    • Orthopedic surgery
    • Biomechanical engineering
    • Bone healing and fracture repair

    Background:

    • Osteoporotic fractures, particularly distal fibular fractures, present challenges due to poor bone quality affecting fixation and outcomes.
    • Previous biomechanical studies often used destructive testing, which may not accurately reflect clinical failure modes in osteoporotic bone.

    Purpose of the Study:

    • To compare the biomechanical performance of a lateral locked construct versus two distinct nonlocking constructs in an osteoporotic segmental fibula defect model.
    • To evaluate construct stiffness, rotational displacement, and screw insertion torque under cyclic loading.

    Main Methods:

    • Eighteen adult cadaveric ankles were randomized into three groups: one-third tubular plate with nonlocking screws, precontoured fibular plate with nonlocking screws, and precontoured plate with locking screws.
    • Constructs were subjected to non-destructive cyclic loading (2.5 Nm external rotation for 10,000 cycles).
    • Primary outcome was change in construct stiffness; secondary outcomes included rotational displacement and insertion torque.

    Main Results:

    • The one-third tubular plate showed a significantly greater increase in stiffness compared to both precontoured nonlocking and locking plates.
    • No significant differences in maximal external rotation were observed among the three construct types.
    • While proximal screw loosening was similar across groups, distal nonlocking constructs exhibited significantly greater loss of insertion torque compared to the locking construct.

    Conclusions:

    • The study found no biomechanical evidence to support the routine use of locking plates over nonlocking plates in osteoporotic fibula fractures.
    • Nonlocking constructs, particularly the precontoured plate, demonstrated comparable or superior performance in key biomechanical parameters under cyclic loading.
    • Further clinical correlation is needed, but these findings challenge the assumption that locking constructs are always necessary for osteoporotic distal fibula fixation.