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Updated: May 7, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Updates in the general approach to the pediatric poisoned patient
Fermin Barrueto1, Rajender Gattu, Maryann Mazer-Amirshahi
1Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Emergency Medicine, Upper Chesapeake Health Systems, Bel Air, MD, USA.
Insights
Poison prevention is crucial for protecting children from toxic substances. Prompt evaluation, including history and examination, guides effective treatment for potential poisonings.
Area of Science:
- Pediatrics
- Toxicology
- Emergency Medicine
Background:
- Poison prevention is vital for safeguarding vulnerable populations, particularly children, from life-threatening toxins.
- Accidental toxic exposures in children necessitate a thorough and systematic approach to evaluation and management.
Purpose of the Study:
- To outline the essential components of evaluating a child with suspected toxic exposure.
- To emphasize the importance of consulting poison centers and medical toxicologists for expert guidance.
Main Methods:
- Detailed patient history, including exposure specifics, ingestions, and recreational activities.
- Comprehensive physical examination to identify signs of toxicity.
- Review of current medical literature and treatment guidelines.
Main Results:
- Accurate exposure history and physical findings are critical for diagnosis.
- Evolving research continuously refines treatment strategies for pediatric poisonings.
- Poison centers provide invaluable support in managing complex cases.
Conclusions:
- A meticulous evaluation is fundamental for diagnosing and managing pediatric poisonings.
- Collaboration with poison control experts ensures access to the latest research-based treatment recommendations.
- Ongoing advancements in toxicology enhance the safety and efficacy of interventions for children.
Abstract:
Poison prevention remains essential to prevent the most vulnerable population from becoming exposed to potentially lethal toxins. The evaluation of a child presumed to have been exposed to a toxic substance should include a precise history of the exposure, a physical examination, and knowledge of current ingestions and recreational practices. New treatments and research guiding therapy continue to evolve. Poison centers and medical toxicologists can be consulted to assist with the diagnosis of medicinal/drug overdoses, for advice about the pitfalls inherent in stabilizing children who have been exposed to toxic compounds, and for treatment recommendations based on the latest research.
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Pharmaceutical Poisoning: Treatment Strategies
Pharmaceutical Poisoning: Potential Scenarios
Prevention of Further Absorption of Poison
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Drug Dosing: Infants and Children
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
