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Updated: May 7, 2026
06:18
An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Perspective on hormone therapy 10 years after the WHI
1Yale University School of Medicine, Department of Obstetrics, Gynecology & Reproductive Sciences, 333 Cedar Street, New Haven, CT 06477, United States.
Maturitas
|October 8, 2013
Summary
The Women's Health Initiative (WHI) trials revolutionized menopause management. A decade after their results, our understanding and clinical practice have transformed significantly.
Area of Science:
- Women's Health
- Endocrinology
- Clinical Trials
Background:
- The Women's Health Initiative (WHI) hormone trials are pivotal, highly debated studies in women's health.
- The 10th anniversary of the WHI results publication marks a decade of significant impact.
Purpose of the Study:
- To summarize the evolution of menopause management over the past 10 years.
- To highlight the transformative changes in understanding and practice following the WHI trial results.
Main Methods:
- Review of scientific literature and clinical practice guidelines.
- Analysis of the impact of WHI trial findings on menopause management strategies.
Main Results:
- A revolutionary shift in the approach to menopause management.
- Enhanced understanding of hormone therapy risks and benefits.
Conclusions:
- The past decade has seen transformative progress in menopause care.
- WHI trial outcomes have fundamentally reshaped clinical practice and women's health research.
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