Advances in the orthopedic management of osteogenesis imperfecta
Dominique Laron1, Nirav K Pandya
1Department of Orthopedic Surgery, University of California San Francisco, Children's Hospital and Research Center Oakland, 747 52nd Street, Oakland, CA 94609, USA.
Abstract:
The long-established study of osteogenesis imperfecta (OI) has opened a realm of scientific research surrounding connective tissue disorders. Over the past decade alone there have been vast advancements in the understanding of the underlying genetic variations of this disease, pharmacologic treatments, and the technological and surgical options for fracture deformity. It is important to appreciate the progressive nature of the advances concerning OI. This article aims to synthesize the expanding evolution of the field surrounding OI over the past decade.
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