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Published on: June 26, 2018
Antitumor characterization of various fractions of Launaea procumbens
Rahmat Ali Khan1, Muhammad Rashid Khan2, Naseer Ali Shah2
1Department of Biotechnology, University of Science and Technology, Bannu, Khyber Pakhtunkhwa, Pakistan Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan rahmatgul_81@yahoo.com.
Abstract:
The antitumor activity of various six fractions of Launaea procumbens were studied using the potato disk bioassay technique. Three concentrations (10, 100, and 1000 ppm) of all these six fractions were used for characterization of antitumor activity. Among these fractions, methanolic fraction exhibited significant inhibition of crown gall tumors caused by Agrobacterium tumefaciens followed by butanolic fraction. These results revealed that methanolic and butanolic fractions contain bioactive constituents responsible for inhibition of tumor. Further purification and characterization are in progress in our laboratory.
