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Updated: May 7, 2026

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems
Published on: March 3, 2010
Convenient synthesis of a highly soluble and stable phosphorescent platinum porphyrin dye
Yaroslav Zems1, Andrey G Moiseev, Dmitrii F Perepichka
1Department of Chemistry, McGill University , 801 Sherbrooke Street West, Montreal, Quebec, Canada H3A 0B8.
Abstract:
A new highly soluble platinum porphyrin derivative 10 with suppressed photobleaching is prepared on a multigram scale from inexpensive starting materials. 10 possesses intense absorption bands at λ = 463 nm (log ε = 5.39) and 633 nm (log ε = 5.20) with near-IR emission at 755 nm. Efficient NIR phosphorescence (PLQY = 0.45) and a large Stokes shift (eliminating self-absorption) make it an attractive and readily available material for a number of applications.
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